Patient information
Name:Dimitrios Papageorgiou
Age:13, Sex:male, Diagnosed:7/9/2010 ,Passed away:19/3/2012 Location:Athens,Greece
Diagnosis:DSRCT,abdominal tumors, the largest one 9x9x8,2 between bladder and rectum,enlarged lymph nodes,no distant metastasis, solid organs ok
Hospitals:Agia Sophia,Athens. University klinikum Heidelberg, Germany
Status:no evidence of desease December 2010 Relapse:11/21/2011
Treatment Chemotherapy: EWS96 protocol, consisting of 9 courses, drugs: cyclofosfamide,andriamycin,. actinomycin, vincristine, mesna Maintenance:trofosfamide,idarubicin,etoposide. o-tie Topotecan,etoposide and Valproate acid
Surgeries:1.cytoreductive plus HIPEC with mitomycin D and Cisplatin. All visible tumors removed, as well spleen, lymph nodes, peritoneum, halph of the right diaphragm,a part of intestine, ileostomia and etc.12hours
2.Reparatory surgery 4 hours : ileostomia fixed, biopsies negative
3.Surgery 6 hour, to remove the local reccurencere (relapse)
All surgeries done in Germany
Radiation:IMRT 20 sessions of total abdominal radiation, Germany
Time line
9/7/2010:biopsies, DSRCT, Hickman
9/15/2010:chemotherapy, vincristine, cyclofosfamide, doxorubicin,mesna 1
0/5/2010:chemotherapy
10/28/2010:ct, good response
11/4/2010:chemotherapy
12/11/2010:laparoscopy
12/20/2010:cytoreductive surgery plus HIPEC with mitomycin D and cisplatin,everything was stripped out,ileostomia,
12/30/2010:released from hospital
1/19/2011:abdominal ultrasound, clear
1/20/2011:chemotherapy
2/14/2011:chemotherapy
2/28/2011:ct scan, no evidence of desease
3/8/2011:surgery, ileostomia was fixed, abdominal biopsies were taken
3/14/2011: biopsies negative
3/28/2011:ct scan, no evidence of desease
3/30/2011: chemotherapy
4/26/2011: chemotherapy
5/18/2011: chemotherapy
6/10/2011: chemotherapy
6/30/2011: ct scan, no evidence of desease
7/1/2011: surgery Hickman removed
7/2/2011: o-tie chemotherapy, trofosfamide and idarubicin
8/6/2011: chemotherapy, trofosfamide and etoposide
9/29/2011:chemotherapy, trofosfamide and idarubicin
10/24/2011:chemotherapy
11/15/2011:chemotherapy
11/21/2011:ct scan,relapse, three lymph nodes enlarged, thorax ct ok
12/6/2011:surgery, removed three retroperitoneal very small tumors and lymph nodes, biopsies were taken from the abdominal cavity
12/15/2011:biopsies negative, lymph nodes were not infiltrated
1/3/2012: IMRT 20 sessions total abdominal 2/2/2012: radiation finished
2/14/2012:abdominal ct scan clear, but thorax ct revealed large mediastinal tumor, fungal infection and enlarged lymph nodes,head ct scan showed multiple lumps in the hairy skin of the head
2/17/2012: chemotherapy, vincristine and temodar
3/6/2012: chemotherapy, topotecane and etoposide
3/15/2012: breathing problems and chest pain
3/19/2012: passed away WIkia DSRCT DSRCT




















